10 Difference between Prokaryotic and Eukaryotic Translation

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Points of ComparisonProkaryotic TranslationEukaryotic Translation
DefinitionThe translation and transcription processes are synchronized.The translation and transcription processes are discontinuous.
mRNACytoplasmNucleus
Cap initiationCap-independentBoth Cap-dependent and Cap-independent
Performed by70S ribosomes80S ribosomes
Stability of mRNAUnstableStable
Ribosomes30S & 50S = 70S40S & 60S = 80S
Lifespan of mRNAA few seconds to 2 minutesA few hours to days
OccurrenceNo definite phaseG1 and G2 phase of the cell cycle
ProcessFastSlow
Release factorRF1, RF2eRF
Initiation factors39

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