| Glycolysis | Krebs Cycle |
|---|
| The location where the process occurs is the cell’s cytoplasm. | The location where the process occurs is the cell’s mitochondria. |
| It takes place in all the living organisms | It takes place only in the aerobes |
| The carbon dioxide is not evolved during this process. | The carbon dioxide is evolved during this process. |
| It requires two ATP molecules to substance molecules for the initial phosphorylation. | It does not require any ATP. |
| It takes place in a linear sequence. | It takes place in a cyclic sequence. |
| It does not need oxygen. | It needs oxygen. |
| In this process, 4 molecules of ATP are generated by one molecule of glucose through substrate-level phosphorylation | In this process, 2 molecules of ATP and GTP are generated by two molecules of acetyl residues through substrate-level phosphorylation |
| It yields two molecules of pyruvate with the action of breaking down glucose and is the first step of respiration. | It forms water and carbon dioxide by degrading the pyruvate and is the second step of respiration. |
| For the glucose breaking down every time, it results in the formation of two molecules of NADH and ATP each. | For every molecule of acetyl-CoA being oxidised, it results in the two molecules of FADH2 and NADH. |